NIH P50 ARTICLES

(NIH P50-GM60338)

*  Credit given to NIH

 

  1. Chrysopoulo, M.T.; Jeschke, M.G.; Ramirez, R.J.; Barrow, R.E.; Herndon, D.N.  Growth hormone attenuates tumor necrosis factor a in burned children.  Arch. Surg. 134(3):283-286; 1999.
  2. Sheffield-Moore, M.; Urban, R.J.; Wolf, S.E.; Jiang, J.; Catlin, D.H.; Herndon, D.N.; Wolfe, R.R.; Ferrando, A.A.  Short-term oxandrolone administration stimulates net muscle synthesis in young men*.  J. Clin. Endocrinol. Metabol. 84(8):2705-2711; 1999.
  3. Barret, J.P.; Dziewulski, P.; Wolf, S.E.; Desai, M.H.; Herndon, D.N.  Effects of recombinant human growth hormone on burn scar development.  Plast. Reconstr. Surg. 104(3):726-729; 1999.
  4. Low, J.F.A.; Herndon, D.N.; Barrow, R.E.  Effect of growth hormone on growth delay in burned children: a 3-year follow- up study.  Lancet 354(9192):1789; 1999.
  5. *Hart, D.W.; Wolf, S.E.; Chinkes, D.L.; Gore, D.C.; Mlcak, R.P.; Beauford, R.B.; Obeng, M.K.; Lal, S.; Gold, W.F.; Wolfe, R.R.; Herndon, D.N.  Determinants of skeletal muscle catabolism after severe burn.  Ann. Surg. 232(4):455-465; 2000.
  6. *Hart, D.W.; Wolf, S.E.; Mlcak, R.; Chinkes, D.L.; Ramzy, P.I.; Obeng, M.K.; Wolfe, R.R.; Herndon, D.N.  Persistence of muscle catabolism after severe burn.  Surgery 128(2):312-319; 2000.
  7. *Hart, D.W.; Wolf, S.E.; Chinkes, D.L.; Lal, S.O.; Beauford, R.B.; Celis, M.; Wolfe, R.R.; Herndon, D.N.  Anti-catabolic synergism between growth hormone and propranolol after burn.  Surg. Forum 51:196-197; 2000.
  8. Lal, S.O.; Herndon, D.N.  Recombinant human growth hormone to treat osteopenia and growth delay after major burns in children.  5th World Congress on Trauma, Shock, Inflammation and Sepsis 859-861; 2000.
  9. Volpi, E.; Jeschke, M.G.; Herndon, D.N.; Wolfe, R.R. Measurement of skin breakdown in a rat model.  Am. J. Physiol. Endocrinol. Metab. 279:E900-E906; 2000.
  10. Biolo, G.; Fleming, R.Y.; Maggi, S.P.; Nguyen, T.T.; Herndon, D.N.; Wolfe, R.R. Inhibition of muscle glutamine formation in hypercatabolic patients.  Clin. Sci. (Colch) 99:189-194; 2000.
  11. *Hart, D.W.; Wolf, S.E.; Ramzy, P.I.; Beauford, R.B.; Ferrando, A.A.; Wolfe, R.R.; Herndon, D.N.  Anabolic effects of oxandrolone following severe burn.  Ann. Surg. 233:556-564; 2001.
  12. *Hart, D.W.; Wolf, S.E.; Zhang, X.J.; Chinkes, D.L.; Buffalo, M.C.; Matin, S.I.; DebRoy, M.A.; Wolfe, R.R.; Herndon, D.N.  Efficacy of high-carbohydrate diet in catabolic illness.  Crit. Care. Med. 29(7):1318-1324; 2001.
  13. Low, J.F.A.; Barrow, R.E.; Mittendorfer, B.; Jeschke, M.G.; Chinkes, D.L.; Herndon, D.N.  The effect of short-term growth hormone treatment on growth and energy expenditure in burned children.  Burns 27(5):447-452; 2001.
  14. *Hart, D.W.; Herndon, D.N.; Klein, G.L.; Lee, S.B.; Celis, M.; Mohan, S.; Chinkes, D.L.; Wolf, S.E.  Attenuation of posttraumatic muscle catabolism and osteopenia by long-term growth hormone therapy.  Ann. Surg. 233:827-834; 2001.
  15. *Suman, O.E.; Spies, R.J.; Celis, M.M.; Mlcak, R.P.; Herndon, D.N.  Effect of a 12-wk resistance exercise program on skeletal muscle strength in children with burn injuries.  J. Appl. Physiol. 91:11698-1175; 2001.
  16. Barret, J.P.; Jeschke, M.G.; Herndon, D.N.  Fatty infiltration of the liver in severely burned pediatric patients: Autopsy findings and clinical implications.  J. Trauma 51(4):736-739; 2001.
  17. Ferrando, A.A.; Sheffield-Moore, M.; Wolf, S.E.; Herndon, D.N.; Wolfe, R.R. Testosterone administration in severe burns ameliorates muscle catabolism.  Crit. Care. Med. 29(10):1936-1942; 2001.
  18. *Herndon, D.N.; Hart, D.W.; Wolf, S.E.; Chinkes, D.L.; Wolfe, R.R. Reversal of catabolism by beta-blockade after severe burns.  New Engl. J. Med. 345(17):1223-1229; 2001.
  19. Jeschke, M.G.; Herndon, D.N.; Ebener, C.; Barrow, R.E.; Jauch, K.W.  Nutritional intervention high in vitamins, protein, amino acids, and ω3 fatty acids improves protein metabolism during the hypermetabolic state after thermal injury.  Arch. Surg. 136:1301-1306; 2001.
  20. *Hart, D.W.; Wolf, S.E.; Herndon, D.N.; Chinkes, D.L.; Lal, S.O.; Obeng, M.K.; Beauford, R.B.; Mlcak, R.P.  Energy expenditure and caloric balance after burn: Increased feeding leads to fat rather than lean mass accretion.  Ann. Surg. 235(1):152-161; 2002.
  21. *Klein G.L.; Langman C.B.; Herndon, D.N.  Vitamin D depletion following burn injury in children: A possible factor in post-burn osteopenia.  J. Trauma 52(2):346-350; 2002.
  22. Maykel, J.A.; Pazirandeh, S.; Bistrian, B.R.; Wolf, S.E.; Wolfe, R.R.; Herndon, D.N.  Beta-blockade and severe burns.  N. Engl. J. Med. 346:707-708; 2002.
  23. *Suman, O.E.; Mlcak, R.P.; Herndon, D.N.  Effect of exercise training on pulmonary function in children with thermal injury.  J. Burn Care Rehabil. 23(4):288-293; 2002.
  24. Morio, B.; Irtun, O.; Herndon, D.N.; Wolfe, R.R. Propranolol decrease splanchnic triacyglycerol storage in burn patients receiving a high-carbohydrate diet.  Ann. Surg. 236(2):218-225; 2002.
  25. Gore, D.C.; Wolf, S.E.; Herndon, D.N.; Wolfe, R.R. Relative influence of glucose and insulin on peripheral amino acid metabolism in severely burned patients.  JPEN 26(5):271-277; 2002.
  26. Wu, X.W.; Herndon, D.N.; Spies, M.; Sanford, A.P.; Wolf, S.E.  Effects of delayed wound excision and grafting in severely burned children.  Arch. Surg. 137:1049-1054; 2002.
  27. Gore, D.C.; Chinkes, D.L.; Hart, D.W.; Wolf, S.E.; Herndon, D.N.; Sanford, A.P.  Hyperglycemia exacerbates muscle protein catabolism in burn-injured patients.  Crit. Care. Med. 30(11):2438-2442; 2002.
  28. *Thomas, S.J.; Morimoto, K.; Herndon, D.N.; Ferrando, A.A.; Wolfe, R.R.; Klein, G.L.; Wolf, S.E.  The effect of prolonged euglycemic hyperinsulinemia on lean body mass after severe burn.  Surgery 132(2):341-347, 2002.
  29. Biolo, G.; Fleming, R.Y.; Maggi, S.P.; Nguyen, T.T.; Herndon, D.N.  Inverse regulation of protein turnover and amino acid transport in skeletal muscle of hypercatabolic patients.  J. Clin. Endocrinol. Metab. 87(7):3378-3384, 2002.
  30. *Celis, M.M.; Suman, O.E.; Huang, T.T.; Yen, P.; Herndon, D.N.  Effect of a supervised exercise and physiotherapy program on surgical interventions in children with thermal injury.  J. Burn Care Rehabil. 24:57-61, 2003.
  31. Barret, J.P.; Herndon, D.N.  Modulation of inflammatory and catabolic responses in severely burned children by early burn wound excision in the first 24 hours.  Arch. Surg. 138:127-132, 2003.
  32. Gore, D.C.; Chinkes, D.C.; Sanford, A.; Hart, D.W.; Wolf, S.E.; Herndon, D.N.  Influence of fever on the hypermetabolic response in burn-injured children.  Arch. Surg. 138:169-174, 2003.
  33. Wu, X.W.; Herndon, D.N.; Wolf, S.E.  Growth hormone down-regulation of IL-1b and IL-6 induced acute phase protein gene expression is associated with increased gene expression of suppressor of cytokine signal-3 (SOCS-3).  Shock 19(4):314-320, 2003.
  34. *Barrow, R.E.; Dasu, M.R.K.; Ferrando, A.A.; Spies, M.; Thomas, S.J.; Perez-Polo, J.R.; Herndon, D.N.  Gene expression patterns in skeletal muscle of thermally injured children treated with oxandrolone.  Ann. Surg. 237(3):422-428, 2003.
  35. Spies, M.; Herndon, D.N.; Rosenblatt, J.I.; Sanford, A.P.; Wolf, S.E.  Prediction of mortality from catastrophic burns in children.  Lancet 361(9362):989-994, 2003.
  36. *Hart, D.W.; Wolf, S.E.; Chinkes, D.L.; Beauford, R.B.; Mlcak, R.P.; Heggers, J.P.; Wolfe, R.R.; Herndon, D.N.  Effects of early excision and aggressive enteral feeding on hypermetabolism, catabolism, and sepsis after severe burn.  J. Trauma 54(4):755-764, 2003.
  37. Barret, J.P.; Herndon, DN.  Effects of burn wound excision on bacterial colonization and invasion.  Plast. Reconstr. Surg. 111(2):744-50; discussion 751-752, 2003.
  38. Herndon, D.N.  Nutritional and pharmacological support of the metabolic response to injury.  Minerva Anestesiologica 69(4): 264-274, 2003.
  39. *Wolf, S.E.; Thomas, S.J.; Dasu, M.R.K.; Ferrando, A.A.; Chinkes, D.L.; Wolfe, R.R.; Herndon, D.N.  Improved net protein balance, lean mass, and gene expression changes with oxandrolone treatment in the severely burned.  Ann. Surg. 237(6);801-811, 2003.
  40. Connolly, C.M.; Barrow, R.E.; Chinkes, D.L.; Martinez, J.A.; Herndon, D.N.  Recombinant human growth hormone increases thyroid hormone-binding sites in recovering severely burned children.  Shock 19(5):399-403, 2003.
  41. Herndon, D.N.; Dasu, M.R.K.; Wolfe, R.R.; Barrow, R.E.  Gene expression profiles and protein balance in skeletal muscle of burned children after b-adrenergic blockade.  Am. J. Physiol. Endocrinol. Metab. 285: E783-E789, 2003.
  42. *Suman, O.E.; Thomas, S.J.; Wilkins, J.P.; Mlcak, R.P.; Herndon, D.N.  Effect of exogenous growth hormone and exercise on lean mass and muscle function in children with burns. J. Appl. Physiol. 94: 2273-2281, 2003.
  43. *Wilkins, J.P.; Suman, O.E.; Benjamin, D.A.; Herndon, D.N.  Comparison of self-reported and monitored compliance of daily injection of human growth hormone in burned children.  Burns 29(7):697-701, 2003.